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2019 | 2 |
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Page 1
Designing Smaller, Synthetic, Functional Mimetics of Sulfated Glycosaminoglycans as Allosteric Modulators of Coagulation Factors.
J Med Chem. 2023 Apr 13;66(7):4503-4531. doi: 10.1021/acs.jmedchem.3c00132. Epub 2023 Mar 31.
J Med Chem. 2023.
PMID: 37001055
Free PMC article.
Review.
Designing Synthetic, Sulfated Glycosaminoglycan Mimetics That Are Orally Bioavailable and Exhibiting In Vivo Anticancer Activity.
Morla S, Ravikumar O, O'Hara C, Boothello R, Vera A, Abdelfadiel EI, Fayyad R, Afosah DK, Sharon C, Fernandez L, Shah SA, Patel BB, Desai UR.
Morla S, et al. Among authors: abdelfadiel ei.
J Med Chem. 2023 Jan 26;66(2):1321-1338. doi: 10.1021/acs.jmedchem.2c01511. Epub 2023 Jan 12.
J Med Chem. 2023.
PMID: 36634271
Free PMC article.
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A Unique Nonsaccharide Mimetic of Heparin Hexasaccharide Inhibits Colon Cancer Stem Cells via p38 MAP Kinase Activation.
Boothello RS, Patel NJ, Sharon C, Abdelfadiel EI, Morla S, Brophy DF, Lippman HR, Desai UR, Patel BB.
Boothello RS, et al. Among authors: abdelfadiel ei.
Mol Cancer Ther. 2019 Jan;18(1):51-61. doi: 10.1158/1535-7163.MCT-18-0104. Epub 2018 Oct 18.
Mol Cancer Ther. 2019.
PMID: 30337351
Free PMC article.
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A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.
Al-Horani RA, Abdelfadiel EI, Afosah DK, Morla S, Sistla JC, Mohammed B, Martin EJ, Sakagami M, Brophy DF, Desai UR.
Al-Horani RA, et al. Among authors: abdelfadiel ei.
J Thromb Haemost. 2019 Dec;17(12):2110-2122. doi: 10.1111/jth.14606. Epub 2019 Sep 10.
J Thromb Haemost. 2019.
PMID: 31397071
Free PMC article.
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